CHEMOINTEL™ Foundational Research

Foundational research on the MICK Assay the predecessor to ChemoINTEL™ is summarized by the published articles below.

RESEARCH (click on PDF icons or file name):

Salom, E., Penalver, M., Homesley, H., Burrell, M., Garrett, A., Presant, C. A., & Rutledge, J. (2012). Correlation of pretreatment drug induced apoptosis in ovarian cancer cells with patient survival and clinical response. Journal of Translational Medicine, 10(62), 1-8.

Bosserman, L. D., Rajurka, S. P., Rogers, K., Davidson, D. C., Chernick, M., Hallquist, A., Malouf, D., & Presant, C. A. (2012).  Correlation of drug-induced apoptosis assay results with oncologist treatment decisions and patient response and survival with oncologist treatment decisions and patient response and survival. Cancer, 118, 4877-4883.

Strickland., S. A., Raptis, A., Hallquist, A., Rutledge, J., Chernick, M., Perree, M., Tablott, M. S., & Presant, C. A. (2013). Correlation of the microculture-kinetic drug-induced apoptosis assay with patient outcomes in initial treatment of adult acute myelocytic leukemia. Leukemia & Lymphoma, 54(3), 528-534.

Bosserman, L. D., Rogers, K., Willis, C., Davidson, D., Whitworth, P., Karimi, M., Upadhyaya, G., Rutledge, J., Hallquist, A., Perree, M., & Presant, C. A. (2015).  Application of a Drug-Induced Apoptosis Assay to Identify Treatment Strategies in Recurrent or Metastatic Breast Cancer.PLoS One, 10(5), doi: 10.1371/journal.pone.0122609

Ballard, K. S., Homesley, H. D., Hodson, C., Presant, C. A., Rutledge, J., Hallquist, A., & Perree, M. (2010) Endometrial Carcinoma In-Vitro Chemosensitivity Testing of Single and Combination Chemotherapy Regimens Using the Novel Microculture Kinetic (MiCK) Apoptosis Assay: Implications for Endometrial Cancer Treatment. Journal of Gynecology Oncology, 21(1),45-49, doi: 10.3802/jgo.2010.21.1.45